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Among these is the receptor tyrosine kinase (RTK)/Rat sarcoma virus (RAS)/ phosphoinositide 3-kinase (PI3K) pathway, which drives proliferation and survival, in part, in a mammalian target of rapamycin (mTOR)-dependent manner [26]

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Cysteine is the limiting substrate for GSH synthesis in neurons (Dringen, Pfeiffer, et al